Neutrophil extracellular traps and common carotid intema media thickness as predictors of cardio vascular risk in patients with systemic lupus erythematous

Background: Neutrophil extracellular traps (NETs) are chromatin complexes of cell-free DNA and histones, with attached neutrophil granular proteins which trap kill infectious microbes. NETs essential in host defense, also linked to inflammation autoimmunity, including systemic lupus erythematosus (SLE) recently emerged as contributor arterial venous thrombosis. Common carotid intema media thickness (CIMT) used commonly indicator for subclinical atherosclerosis myocardial infarction rheumatic diseases. In the current study, we investigated, role NET CIMT human SLE their association disease activity cardiovascular complications.Methods: Levels (human myeloperoxidase-DNA complexes) were analyzed plasma from 40 patients healthy individuals using MPO ELISA kit, risk was assessed these groups by CIMT.Results: Comparison between both showed significant difference level MPO) (p< 0.01), positive correlation complications.Conclusion: could be good predictors patients.